Recurrent EZH1 mutations are a second hit in autonomous thyroid adenomas
Recurrent EZH1 mutations are a second hit in autonomous thyroid adenomas
About this item
Full title
Author / Creator
Calebiro, Davide , Grassi, Elisa S. , Eszlinger, Markus , Ronchi, Cristina L. , Godbole, Amod , Bathon, Kerstin , Guizzardi, Fabiana , de Filippis, Tiziana , Krohn, Knut , Jaeschke, Holger , Schwarzmayr, Thomas , Bircan, Rifat , Gozu, Hulya Iliksu , Sancak, Seda , Niedziela, Marek , Strom, Tim M. , Fassnacht, Martin , Persani, Luca and Paschke, Ralf
Publisher
United States: American Society for Clinical Investigation
Journal title
Language
English
Formats
Publication information
Publisher
United States: American Society for Clinical Investigation
Subjects
More information
Scope and Contents
Contents
Autonomous thyroid adenomas (ATAs) are a frequent cause of hyperthyroidism. Mutations in the genes encoding the TSH receptor (TSHR) or the Gs protein α subunit (GNAS) are found in approximately 70% of ATAs. The involvement of other genes and the pathogenesis of the remaining cases are presently unknown. Here, we performed whole-exome sequencing in...
Alternative Titles
Full title
Recurrent EZH1 mutations are a second hit in autonomous thyroid adenomas
Authors, Artists and Contributors
Author / Creator
Grassi, Elisa S.
Eszlinger, Markus
Ronchi, Cristina L.
Godbole, Amod
Bathon, Kerstin
Guizzardi, Fabiana
de Filippis, Tiziana
Krohn, Knut
Jaeschke, Holger
Schwarzmayr, Thomas
Bircan, Rifat
Gozu, Hulya Iliksu
Sancak, Seda
Niedziela, Marek
Strom, Tim M.
Fassnacht, Martin
Persani, Luca
Paschke, Ralf
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5004945
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5004945
Other Identifiers
ISSN
0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI84894
