Tie1: an orphan receptor provides context for angiopoietin-2/Tie2 signaling
Tie1: an orphan receptor provides context for angiopoietin-2/Tie2 signaling
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Publisher
United States: American Society for Clinical Investigation
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Language
English
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Publisher
United States: American Society for Clinical Investigation
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Scope and Contents
Contents
Angiopoietin-1/Tie2 (ANG1/Tie2) signaling is well documented as regulating angiogenesis and vessel maturation. This pathway is complicated by involvement of the orphan receptor Tie1, which has been implicated as both a positive and negative regulator of ANG1/Tie2 signaling, and ANG2, which can serve as both a Tie2 agonist and antagonist, depending...
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Full title
Tie1: an orphan receptor provides context for angiopoietin-2/Tie2 signaling
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5004958
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5004958
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ISSN
0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI89963