T helper 1 immunity requires complement-driven NLRP3 inflammasome activity in CD4⁺ T cells
T helper 1 immunity requires complement-driven NLRP3 inflammasome activity in CD4⁺ T cells
About this item
Full title
Author / Creator
Arbore, Giuseppina , West, Erin E. , Spolski, Rosanne , Robertson, Avril A. B. , Klos, Andreas , Rheinheimer, Claudia , Dutow, Pavel , Woodruff, Trent M. , Yu, Zu Xi , O'Neill, Luke A. , Coll, Rebecca C. , Sher, Alan , Leonard, Warren J. , Köhl, Jörg , Monk, Pete , Cooper, Matthew A. , Arno, Matthew , Afzali, Behdad , Lachmann, Helen J. , Cope, Andrew P. , Mayer-Barber, Katrin D. and Kemper, Claudia
Publisher
United States: American Association for the Advancement of Science
Journal title
Language
English
Formats
Publication information
Publisher
United States: American Association for the Advancement of Science
Subjects
More information
Scope and Contents
Contents
The classical view of immune activation is that innate immune cells, such as macrophages and dendritic cells, recognize invading microbes and then alert adaptive immune cells, such as T cells, to respond. Arbore
et al.
now show that innate and adaptive immunity converge in human and mouse T cells. Activated T cells express components of the c...
Alternative Titles
Full title
T helper 1 immunity requires complement-driven NLRP3 inflammasome activity in CD4⁺ T cells
Authors, Artists and Contributors
Author / Creator
West, Erin E.
Spolski, Rosanne
Robertson, Avril A. B.
Klos, Andreas
Rheinheimer, Claudia
Dutow, Pavel
Woodruff, Trent M.
Yu, Zu Xi
O'Neill, Luke A.
Coll, Rebecca C.
Sher, Alan
Leonard, Warren J.
Köhl, Jörg
Monk, Pete
Cooper, Matthew A.
Arno, Matthew
Afzali, Behdad
Lachmann, Helen J.
Cope, Andrew P.
Mayer-Barber, Katrin D.
Kemper, Claudia
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5015487
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5015487
Other Identifiers
ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.aad1210
