Synthesis and mechanisms of action of novel harmine derivatives as potential antitumor agents
Synthesis and mechanisms of action of novel harmine derivatives as potential antitumor agents
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
A series of novel harmine derivatives bearing a benzylindine substituent in position-1 of β-carboline ring were synthesized and evaluated as antitumor agents. The N2-benzylated β-carboline derivatives 3a–g represented the most interesting anticancer activities and compound 3c was found to be the most active agent to diverse cancer cell lines such a...
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Full title
Synthesis and mechanisms of action of novel harmine derivatives as potential antitumor agents
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5021947
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5021947
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/srep33204
