Imaging of cerebral α4β2 nicotinic acetylcholine receptors with (−)-[18F]Flubatine PET: Implementati...
Imaging of cerebral α4β2 nicotinic acetylcholine receptors with (−)-[18F]Flubatine PET: Implementation of bolus plus constant infusion and sensitivity to acetylcholine in human brain
About this item
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Author / Creator
Hillmer, A.T. , Esterlis, I. , Gallezot, J.D. , Bois, F. , Zheng, M.Q. , Nabulsi, N. , Lin, S.F. , Papke, R.L. , Huang, Y. , Sabri, O. , Carson, R.E. and Cosgrove, K.P.
Publisher
United States: Elsevier Inc
Journal title
Language
English
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Publication information
Publisher
United States: Elsevier Inc
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Scope and Contents
Contents
The positron emission tomography (PET) radioligand (−)-[18F]flubatine is specific to α4β2⁎ nicotinic acetylcholine receptors (nAChRs) and has promise for future investigation of the acetylcholine system in neuropathologies such as Alzheimer's disease, schizophrenia, and substance use disorders. The two goals of this work were to develop a simplifie...
Alternative Titles
Full title
Imaging of cerebral α4β2 nicotinic acetylcholine receptors with (−)-[18F]Flubatine PET: Implementation of bolus plus constant infusion and sensitivity to acetylcholine in human brain
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5026941
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5026941
Other Identifiers
ISSN
1053-8119
E-ISSN
1095-9572
DOI
10.1016/j.neuroimage.2016.07.026
