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Prediction of multidimensional drug dose responses based on measurements of drug pairs

Prediction of multidimensional drug dose responses based on measurements of drug pairs

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5027409

Prediction of multidimensional drug dose responses based on measurements of drug pairs

About this item

Full title

Prediction of multidimensional drug dose responses based on measurements of drug pairs

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2016-09, Vol.113 (37), p.10442-10447

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Finding potent multidrug combinations against cancer and infections is a pressing therapeutic challenge; however, screening all combinations is difficult because the number of experiments grows exponentially with the number of drugs and doses. To address this, we present a mathematical model that predicts the effects of three or more antibiotics or...

Alternative Titles

Full title

Prediction of multidimensional drug dose responses based on measurements of drug pairs

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5027409

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5027409

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1606301113

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