Smac mimetics and innate immune stimuli synergize to promote tumor death
Smac mimetics and innate immune stimuli synergize to promote tumor death
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Publisher
New York: Nature Publishing Group US
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Language
English
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New York: Nature Publishing Group US
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Contents
Synergistic cancer therapies SMAC mimetic compounds synergize with oncolytic viruses and other innate immune stimuli to promote tumor cell death.
Smac mimetic compounds (SMC), a class of drugs that sensitize cells to apoptosis by counteracting the activity of inhibitor of apoptosis (IAP) proteins, have proven safe in phase 1 clinical trials in c...
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Full title
Smac mimetics and innate immune stimuli synergize to promote tumor death
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5030098
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5030098
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ISSN
1087-0156
E-ISSN
1546-1696
DOI
10.1038/nbt.2806
