Genomic analysis of the molecular neuropathology of tuberous sclerosis using a human stem cell model
Genomic analysis of the molecular neuropathology of tuberous sclerosis using a human stem cell model
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Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Scope and Contents
Contents
Tuberous sclerosis complex (TSC) is a genetic disease characterized by benign tumor growths in multiple organs and neurological symptoms induced by mTOR hyperfunction. Because the molecular pathology is highly complex and the etiology poorly understood, we employed a defined human neuronal model with a single mTOR activating mutation to dissect the...
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Full title
Genomic analysis of the molecular neuropathology of tuberous sclerosis using a human stem cell model
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5031259
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5031259
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ISSN
1756-994X
E-ISSN
1756-994X
DOI
10.1186/s13073-016-0347-3
