TALEN-based generation of a cynomolgus monkey disease model for human microcephaly
TALEN-based generation of a cynomolgus monkey disease model for human microcephaly
About this item
Full title
Author / Creator
Ke, Qiong , Li, Weiqiang , Lai, Xingqiang , Chen, Hong , Huang, Lihua , Kang, Zhuang , Li, Kai , Ren, Jie , Lin, Xiaofeng , Zheng, Haiqing , Huang, Weijun , Ma, Yunhan , Xu, Dongdong , Chen, Zheng , Song, Xinming , Lin, Xinyi , Zhuang, Min , Wang, Tao , Zhuang, Fengfeng , Xi, Jianzhong , Mao, Frank Fuxiang , Xia, Huimin , Lahn, Bruce T , Zhou, Qi , Yang, Shihua and Xiang, Andy Peng
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Gene editing in non-human primates may lead to valuable models for exploring the etiologies and therapeutic strategies of genetically based neurological disorders in humans. However, a monkey model of neurological disorders that closely mimics pathological and behavioral deficits in humans has not yet been successfully generated. Micro- cephalin 1...
Alternative Titles
Full title
TALEN-based generation of a cynomolgus monkey disease model for human microcephaly
Authors, Artists and Contributors
Author / Creator
Li, Weiqiang
Lai, Xingqiang
Chen, Hong
Huang, Lihua
Kang, Zhuang
Li, Kai
Ren, Jie
Lin, Xiaofeng
Zheng, Haiqing
Huang, Weijun
Ma, Yunhan
Xu, Dongdong
Chen, Zheng
Song, Xinming
Lin, Xinyi
Zhuang, Min
Wang, Tao
Zhuang, Fengfeng
Xi, Jianzhong
Mao, Frank Fuxiang
Xia, Huimin
Lahn, Bruce T
Zhou, Qi
Yang, Shihua
Xiang, Andy Peng
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5034111
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5034111
Other Identifiers
ISSN
1001-0602
E-ISSN
1748-7838
DOI
10.1038/cr.2016.93
