Etoposide induced cytotoxicity mediated by ROS and ERK in human kidney proximal tubule cells
Etoposide induced cytotoxicity mediated by ROS and ERK in human kidney proximal tubule cells
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Contents
Etoposide (ETO) is a commonly used chemotherapeutic drug that inhibits topoisomerase II activity, thereby leading to genotoxicity and cytotoxicity. However, ETO has limited application due to its side effects on normal organs, especially the kidney. Here, we report the mechanism of ETO-induced cytotoxicity progression in human kidney proximal tubul...
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Full title
Etoposide induced cytotoxicity mediated by ROS and ERK in human kidney proximal tubule cells
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5036097
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5036097
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/srep34064
