Carbonic anhydrase IV inhibits colon cancer development by inhibiting the Wnt signalling pathway thr...
Carbonic anhydrase IV inhibits colon cancer development by inhibiting the Wnt signalling pathway through targeting the WTAP–WT1–TBL1 axis
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Author / Creator
Zhang, Jingwan , Tsoi, Ho , Li, Xiaoxing , Wang, Hua , Gao, Jing , Wang, Kunning , Go, Minnie YY , Ng, Siew C , Chan, Francis KL , Sung, Joseph JY and Yu, Jun
Publisher
England: BMJ Publishing Group LTD
Journal title
Language
English
Formats
Publication information
Publisher
England: BMJ Publishing Group LTD
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Scope and Contents
Contents
ObjectiveWe found that carbonic anhydrase IV (CA4), a member of the carbonic anhydrases, is silenced in colorectal cancer (CRC). We analysed its epigenetic inactivation, biological effects and prognostic significance in CRC.DesignThe biological functions of CA4 were determined by in vitro and in vivo tumorigenicity assays. The CA4 co-operator was i...
Alternative Titles
Full title
Carbonic anhydrase IV inhibits colon cancer development by inhibiting the Wnt signalling pathway through targeting the WTAP–WT1–TBL1 axis
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5036249
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5036249
Other Identifiers
ISSN
0017-5749
E-ISSN
1468-3288
DOI
10.1136/gutjnl-2014-308614
