Stem cell function and stress response are controlled by protein synthesis
Stem cell function and stress response are controlled by protein synthesis
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Whether protein synthesis and cellular stress response pathways interact to control stem cell function is currently unknown. Here we show that mouse skin stem cells synthesize less protein than their immediate progenitors
in vivo,
even when forced to proliferate. Our analyses reveal that activation of stress response pathways drives both a gl...
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Full title
Stem cell function and stress response are controlled by protein synthesis
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5040503
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5040503
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature18282
