Punctuated copy number evolution and clonal stasis in triple-negative breast cancer
Punctuated copy number evolution and clonal stasis in triple-negative breast cancer
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Publisher
New York: Nature Publishing Group US
Journal title
Language
English
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Publisher
New York: Nature Publishing Group US
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Scope and Contents
Contents
Nicholas Navin and colleagues use highly multiplexed single-nucleus sequencing to investigate DNA copy number evolution in patients with triple-negative breast cancer. Their data suggest that most copy number alterations are acquired at the earliest stages of tumor evolution in short punctuated bursts, followed by stable clonal expansions that form...
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Full title
Punctuated copy number evolution and clonal stasis in triple-negative breast cancer
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5042845
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5042845
Other Identifiers
ISSN
1061-4036
E-ISSN
1546-1718
DOI
10.1038/ng.3641
