Disruption of ArhGAP15 results in hyperactive Rac1, affects the architecture and function of hippoca...
Disruption of ArhGAP15 results in hyperactive Rac1, affects the architecture and function of hippocampal inhibitory neurons and causes cognitive deficits
About this item
Full title
Author / Creator
Zamboni, Valentina , Armentano, Maria , Sarò, Gabriella , Ciraolo, Elisa , Ghigo, Alessandra , Germena, Giulia , Umbach, Alessandro , Valnegri, Pamela , Passafaro, Maria , Carabelli, Valentina , Gavello, Daniela , Bianchi, Veronica , D’Adamo, Patrizia , de Curtis, Ivan , El-Assawi, Nadia , Mauro, Alessandro , Priano, Lorenzo , Ferri, Nicola , Hirsch, Emilio and Merlo, Giorgio R.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
During brain development, the small GTPases Rac1/Rac3 play key roles in neuronal migration, neuritogenesis, synaptic formation and plasticity, via control of actin cytoskeleton dynamic. Their activity is positively and negatively regulated by GEFs and GAPs molecules, respectively. However their
in vivo
roles are poorly known. The
ArhGAP15<...
Alternative Titles
Full title
Disruption of ArhGAP15 results in hyperactive Rac1, affects the architecture and function of hippocampal inhibitory neurons and causes cognitive deficits
Authors, Artists and Contributors
Author / Creator
Armentano, Maria
Sarò, Gabriella
Ciraolo, Elisa
Ghigo, Alessandra
Germena, Giulia
Umbach, Alessandro
Valnegri, Pamela
Passafaro, Maria
Carabelli, Valentina
Gavello, Daniela
Bianchi, Veronica
D’Adamo, Patrizia
de Curtis, Ivan
El-Assawi, Nadia
Mauro, Alessandro
Priano, Lorenzo
Ferri, Nicola
Hirsch, Emilio
Merlo, Giorgio R.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5054378
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5054378
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/srep34877
