Structural insights into conformational stability of both wild-type and mutant EZH2 receptor
Structural insights into conformational stability of both wild-type and mutant EZH2 receptor
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Publisher
London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Contents
Polycomb group (PcG) proteins have been observed to maintain the pattern of histone by methylation of the histone tail responsible for the gene expression in various cellular processes, of which enhancer of zeste homolog 2 (EZH2) acts as tumor suppressor. Overexpression of EZH2 results in hyper activation found in a variety of cancer. Point mutatio...
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Full title
Structural insights into conformational stability of both wild-type and mutant EZH2 receptor
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5054529
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5054529
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/srep34984
