Biophysical determinants for cellular uptake of hydrocarbon-stapled peptide helices
Biophysical determinants for cellular uptake of hydrocarbon-stapled peptide helices
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Publisher
New York: Nature Publishing Group US
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Language
English
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New York: Nature Publishing Group US
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Contents
Detailed biophysical, microscopy, and statistical analyses of hydrocarbon-stapled peptide variants revealed how a combination of critical parameters such as hydrophobicity, α-helicity and isoelectric point influence cellular permeability.
Hydrocarbon-stapled peptides are a class of bioactive alpha-helical ligands developed to dissect and target...
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Full title
Biophysical determinants for cellular uptake of hydrocarbon-stapled peptide helices
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5055751
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5055751
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ISSN
1552-4450
E-ISSN
1552-4469
DOI
10.1038/nchembio.2153