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Critical reappraisal confirms that Mitofusin 2 is an endoplasmic reticulum–mitochondria tether

Critical reappraisal confirms that Mitofusin 2 is an endoplasmic reticulum–mitochondria tether

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5056088

Critical reappraisal confirms that Mitofusin 2 is an endoplasmic reticulum–mitochondria tether

About this item

Full title

Critical reappraisal confirms that Mitofusin 2 is an endoplasmic reticulum–mitochondria tether

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2016-10, Vol.113 (40), p.11249-11254

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

The discovery of the multiple roles of mitochondria–endoplasmic reticulum (ER) juxtaposition in cell biology often relied upon the exploitation of Mitofusin (Mfn) 2 as an ER–mitochondria tether. However, this established Mfn2 function was recently questioned, calling for a critical re-evaluation of Mfn2’s role in ER–mitochondria cross-talk. Electro...

Alternative Titles

Full title

Critical reappraisal confirms that Mitofusin 2 is an endoplasmic reticulum–mitochondria tether

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5056088

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5056088

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1606786113

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