A Naturally Occurring Antibody Fragment Neutralizes Infectivity of Diverse Infectious Agents
A Naturally Occurring Antibody Fragment Neutralizes Infectivity of Diverse Infectious Agents
About this item
Full title
Author / Creator
Polonelli, Luciano , Ciociola, Tecla , Elviri, Lisa , Zanello, Pier Paolo , Giovati, Laura , Arruda, Denise C. , Muñoz, Julián E. , Mortara, Renato A. , Morace, Giulia , Borghi, Elisa , Galati, Serena , Marin, Oriano , Casoli, Claudio , Pilotti, Elisabetta , Ronzi, Paola , Travassos, Luiz R. , Magliani, Walter and Conti, Stefania
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
A phosphorylated peptide, named K40H, derived from the constant region of IgMs was detected in human serum by liquid chromatography coupled to high-resolution mass spectrometry. Synthetic K40H proved to exert a potent
in vitro
activity against fungal pathogens, and to inhibit HIV-1 replication
in vitro
and
ex vivo
. It also showed...
Alternative Titles
Full title
A Naturally Occurring Antibody Fragment Neutralizes Infectivity of Diverse Infectious Agents
Authors, Artists and Contributors
Author / Creator
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5057116
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5057116
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/srep35018
