Circulating histones are major mediators of systemic inflammation and cellular injury in patients wi...
Circulating histones are major mediators of systemic inflammation and cellular injury in patients with acute liver failure
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Author / Creator
Wen, Zongmei , Lei, Zhen , Yao, Lu , Jiang, Ping , Gu, Tao , Ren, Feng , Liu, Yan , Gou, Chunyan , Li, Xiuhui and Wen, Tao
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Acute liver failure (ALF) is a life-threatening systemic disorder. Here we investigated the impact of circulating histones, recently identified inflammatory mediators, on systemic inflammation and liver injury in murine models and patients with ALF. We analyzed histone levels in blood samples from 62 patients with ALF, 60 patients with chronic live...
Alternative Titles
Full title
Circulating histones are major mediators of systemic inflammation and cellular injury in patients with acute liver failure
Authors, Artists and Contributors
Author / Creator
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5059889
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5059889
Other Identifiers
ISSN
2041-4889
E-ISSN
2041-4889
DOI
10.1038/cddis.2016.303