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Circulating histones are major mediators of systemic inflammation and cellular injury in patients wi...

Circulating histones are major mediators of systemic inflammation and cellular injury in patients wi...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5059889

Circulating histones are major mediators of systemic inflammation and cellular injury in patients with acute liver failure

About this item

Full title

Circulating histones are major mediators of systemic inflammation and cellular injury in patients with acute liver failure

Publisher

London: Nature Publishing Group UK

Journal title

Cell death & disease, 2016-09, Vol.7 (9), p.e2391-e2391

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Acute liver failure (ALF) is a life-threatening systemic disorder. Here we investigated the impact of circulating histones, recently identified inflammatory mediators, on systemic inflammation and liver injury in murine models and patients with ALF. We analyzed histone levels in blood samples from 62 patients with ALF, 60 patients with chronic live...

Alternative Titles

Full title

Circulating histones are major mediators of systemic inflammation and cellular injury in patients with acute liver failure

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5059889

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5059889

Other Identifiers

ISSN

2041-4889

E-ISSN

2041-4889

DOI

10.1038/cddis.2016.303

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