Hypoxia-independent gene expression signature associated with radiosensitisation of prostate cancer...
Hypoxia-independent gene expression signature associated with radiosensitisation of prostate cancer cell lines by histone deacetylase inhibition
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Background:
Histone deacetylase inhibitors (HDACis) like vorinostat are promising radiosensitisers in prostate cancer, but their effect under hypoxia is not known. We investigated gene expression associated with radiosensitisation of normoxic and hypoxic prostate cancer cells by vorinostat.
Methods:
Cells were exposed to vorinostat under n...
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Full title
Hypoxia-independent gene expression signature associated with radiosensitisation of prostate cancer cell lines by histone deacetylase inhibition
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5061908
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5061908
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ISSN
0007-0920
E-ISSN
1532-1827
DOI
10.1038/bjc.2016.278