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Microenvironment complexity and matrix stiffness regulate breast cancer cell activity in a 3D in vit...

Microenvironment complexity and matrix stiffness regulate breast cancer cell activity in a 3D in vit...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5062115

Microenvironment complexity and matrix stiffness regulate breast cancer cell activity in a 3D in vitro model

About this item

Full title

Microenvironment complexity and matrix stiffness regulate breast cancer cell activity in a 3D in vitro model

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2016-10, Vol.6 (1), p.35367-35367, Article 35367

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Three-dimensional (3D) cell cultures represent fundamental tools for the comprehension of cellular phenomena both in normal and in pathological conditions. In particular, mechanical and chemical stimuli play a relevant role on cell fate, cancer onset and malignant evolution. Here, we use mechanically-tuned alginate hydrogels to study the role of su...

Alternative Titles

Full title

Microenvironment complexity and matrix stiffness regulate breast cancer cell activity in a 3D in vitro model

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5062115

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5062115

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/srep35367

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