Microenvironment complexity and matrix stiffness regulate breast cancer cell activity in a 3D in vit...
Microenvironment complexity and matrix stiffness regulate breast cancer cell activity in a 3D in vitro model
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Three-dimensional (3D) cell cultures represent fundamental tools for the comprehension of cellular phenomena both in normal and in pathological conditions. In particular, mechanical and chemical stimuli play a relevant role on cell fate, cancer onset and malignant evolution. Here, we use mechanically-tuned alginate hydrogels to study the role of su...
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Microenvironment complexity and matrix stiffness regulate breast cancer cell activity in a 3D in vitro model
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5062115
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5062115
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/srep35367