Prognostic impact of KRAS, NRAS, BRAF, and PIK3CA mutations in primary colorectal carcinomas: a popu...
Prognostic impact of KRAS, NRAS, BRAF, and PIK3CA mutations in primary colorectal carcinomas: a population-based study
About this item
Full title
Author / Creator
Palomba, Grazia , Doneddu, Valentina , Cossu, Antonio , Paliogiannis, Panagiotis , Manca, Antonella , Casula, Milena , Colombino, Maria , Lanzillo, Annamaria , Defraia, Efisio , Pazzola, Antonio , Sanna, Giovanni , Putzu, Carlo , Ortu, Salvatore , Scartozzi, Mario , Ionta, Maria Teresa , Baldino, Giovanni , Sarobba, Giuseppina , Capelli, Francesca , Sedda, Tito , Virdis, Luciano , Barca, Michela , Gramignano, Giulia , Budroni, Mario , Tanda, Francesco and Palmieri, Giuseppe
Publisher
England: BioMed Central Ltd
Journal title
Language
English
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Publication information
Publisher
England: BioMed Central Ltd
Subjects
More information
Scope and Contents
Contents
Activation of oncogenes downstream the EGFR gene contributes to colorectal tumorigenesis and determines the sensitivity to anti-EGFR treatments. The aim of this study was to evaluate the prognostic value of KRAS, BRAF, NRAS and PIK3CA mutations in a large collection of CRC patients from genetically-homogeneous Sardinian population.
A total of 12...
Alternative Titles
Full title
Prognostic impact of KRAS, NRAS, BRAF, and PIK3CA mutations in primary colorectal carcinomas: a population-based study
Authors, Artists and Contributors
Author / Creator
Doneddu, Valentina
Cossu, Antonio
Paliogiannis, Panagiotis
Manca, Antonella
Casula, Milena
Colombino, Maria
Lanzillo, Annamaria
Defraia, Efisio
Pazzola, Antonio
Sanna, Giovanni
Putzu, Carlo
Ortu, Salvatore
Scartozzi, Mario
Ionta, Maria Teresa
Baldino, Giovanni
Sarobba, Giuseppina
Capelli, Francesca
Sedda, Tito
Virdis, Luciano
Barca, Michela
Gramignano, Giulia
Budroni, Mario
Tanda, Francesco
Palmieri, Giuseppe
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5064898
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5064898
Other Identifiers
ISSN
1479-5876
E-ISSN
1479-5876
DOI
10.1186/s12967-016-1053-z