24-Hydroxycholesterol participates in pancreatic neuroendocrine tumor development
24-Hydroxycholesterol participates in pancreatic neuroendocrine tumor development
About this item
Full title
Author / Creator
Soncini, Matias , Corna, Gianfranca , Moresco, Marta , Coltella, Nadia , Restuccia, Umberto , Maggioni, Daniela , Raccosta, Laura , Lin, Chin-Yo , Invernizzi, Francesca , Crocchiolo, Roberto , Doglioni, Claudio , Traversari, Catia , Bachi, Angela , Bernardi, Rosa , Bordignon, Claudio , Gustafsson, Jan-Åke and Russo, Vincenzo
Publisher
United States: National Academy of Sciences
Journal title
Language
English
Formats
Publication information
Publisher
United States: National Academy of Sciences
Subjects
More information
Scope and Contents
Contents
Cells in the tumor microenvironment may be reprogrammed by tumor-derived metabolites. Cholesterol-oxidized products, namely oxysterols, have been shown to favor tumor growth directly by promoting tumor cell growth and indirectly by dampening antitumor immune responses. However, the cellular and molecular mechanisms governing oxysterol generation wi...
Alternative Titles
Full title
24-Hydroxycholesterol participates in pancreatic neuroendocrine tumor development
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5068323
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5068323
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1613332113
