Neuroplasticity-dependent and -independent mechanisms of chronic deep brain stimulation in stressed...
Neuroplasticity-dependent and -independent mechanisms of chronic deep brain stimulation in stressed rats
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Author / Creator
Bambico, F R , Bregman, T , Diwan, M , Li, J , Darvish-Ghane, S , Li, Z , Laver, B , Amorim, B O , Covolan, L , Nobrega, J N and Hamani, C
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Chronic ventromedial prefrontal cortex (vmPFC) deep brain stimulation (DBS) improves depressive-like behaviour in rats via serotonergic and neurotrophic-related mechanisms. We hypothesise that, in addition to these substrates, DBS-induced increases in hippocampal neurogenesis may also be involved. Our results show that stress-induced behavioural de...
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Full title
Neuroplasticity-dependent and -independent mechanisms of chronic deep brain stimulation in stressed rats
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5068759
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5068759
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ISSN
2158-3188
E-ISSN
2158-3188
DOI
10.1038/tp.2015.166