Thromboxane A2 receptor antagonist SQ29548 reduces ischemic stroke-induced microglia/macrophages act...
Thromboxane A2 receptor antagonist SQ29548 reduces ischemic stroke-induced microglia/macrophages activation and enrichment, and ameliorates brain injury
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Thromboxane A2 receptor (TXA2R) activation is thought to be involved in thrombosis/hemostasis and inflammation responses. We have previously shown that TXA2R antagonist SQ29548 attenuates BV2 microglia activation by suppression of ERK pathway, but its effect is not tested
in vivo
. The present study aims to explore the role of TXA2R on microg...
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Thromboxane A2 receptor antagonist SQ29548 reduces ischemic stroke-induced microglia/macrophages activation and enrichment, and ameliorates brain injury
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5075919
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5075919
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/srep35885
