FBXW7 is involved in the acquisition of the malignant phenotype in epithelial ovarian tumors
FBXW7 is involved in the acquisition of the malignant phenotype in epithelial ovarian tumors
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Publisher
England: John Wiley & Sons, Inc
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Language
English
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Publisher
England: John Wiley & Sons, Inc
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Contents
FBXW7 is a ubiquitin ligase that mediates ubiquitylation of oncoproteins, such as c‐Myc, cyclin E, Notch and c‐Jun. FBXW7 is a known tumor‐suppressor gene, and mutations in FBXW7 have been reported in various human malignancies. In this study, we examined the sequences of the FBXW7 and p53 genes in 57 ovarian cancer clinical samples. Interestingly,...
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Full title
FBXW7 is involved in the acquisition of the malignant phenotype in epithelial ovarian tumors
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5084658
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5084658
Other Identifiers
ISSN
1347-9032
E-ISSN
1349-7006
DOI
10.1111/cas.13026
