Assessment of Amino Acid/Drug Transporters for Renal Transport of [ 18 F]Fluciclovine (anti-[ 18 F]F...
Assessment of Amino Acid/Drug Transporters for Renal Transport of [ 18 F]Fluciclovine (anti-[ 18 F]FACBC) in Vitro
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Publisher
Switzerland: MDPI AG
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Language
English
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Publisher
Switzerland: MDPI AG
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Contents
[
F]Fluciclovine (
-1-amino-3-[
F]fluorocyclobutanecarboxylic acid;
-[
F]FACBC), a positron emission tomography tracer used for the diagnosis of recurrent prostate cancer, is transported via amino acid transporters (AATs) with high affinity (
: 97-230 μM). However, the mechanism underlying urinary excretion is unknown. In this stu...
Alternative Titles
Full title
Assessment of Amino Acid/Drug Transporters for Renal Transport of [ 18 F]Fluciclovine (anti-[ 18 F]FACBC) in Vitro
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5085761
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5085761
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ISSN
1422-0067,1661-6596
E-ISSN
1422-0067
DOI
10.3390/ijms17101730
