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CARD9 impacts colitis by altering gut microbiota metabolism of tryptophan into aryl hydrocarbon rece...

CARD9 impacts colitis by altering gut microbiota metabolism of tryptophan into aryl hydrocarbon rece...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5087285

CARD9 impacts colitis by altering gut microbiota metabolism of tryptophan into aryl hydrocarbon receptor ligands

About this item

Full title

CARD9 impacts colitis by altering gut microbiota metabolism of tryptophan into aryl hydrocarbon receptor ligands

Publisher

London: Nature Publishing Group UK

Journal title

Nature Medicine, 2016-06, Vol.22 (6), p.598-605

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Metabolism of tryptophan by the gut microbiota is impaired by deficiencies in
CARD9
, leading to the worsening of colitis.
Complex interactions between the host and the gut microbiota govern intestinal homeostasis but remain poorly understood. Here we reveal a relationship between gut microbiota and caspase recruitment domain family member...

Alternative Titles

Full title

CARD9 impacts colitis by altering gut microbiota metabolism of tryptophan into aryl hydrocarbon receptor ligands

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5087285

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5087285

Other Identifiers

ISSN

1078-8956,1546-170X

E-ISSN

1546-170X,1744-7933

DOI

10.1038/nm.4102

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