In Vivo Selection Yields AAV-B1 Capsid for Central Nervous System and Muscle Gene Therapy
In Vivo Selection Yields AAV-B1 Capsid for Central Nervous System and Muscle Gene Therapy
About this item
Full title
Author / Creator
Choudhury, Sourav R , Fitzpatrick, Zachary , Harris, Anne F , Maitland, Stacy A , Ferreira, Jennifer S , Zhang, Yuanfan , Ma, Shan , Sharma, Rohit B , Gray-Edwards, Heather L , Johnson, Jacob A , Johnson, Aime K , Alonso, Laura C , Punzo, Claudio , Wagner, Kathryn R , Maguire, Casey A , Kotin, Robert M , Martin, Douglas R and Sena-Esteves, Miguel
Publisher
United States: Elsevier Inc
Journal title
Language
English
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Publication information
Publisher
United States: Elsevier Inc
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More information
Scope and Contents
Contents
Adeno-associated viral (AAV) vectors have shown promise as a platform for gene therapy of neurological disorders. Achieving global gene delivery to the central nervous system (CNS) is key for development of effective therapies for many of these diseases. Here we report the isolation of a novel CNS tropic AAV capsid, AAV-B1, after a single round of...
Alternative Titles
Full title
In Vivo Selection Yields AAV-B1 Capsid for Central Nervous System and Muscle Gene Therapy
Authors, Artists and Contributors
Author / Creator
Fitzpatrick, Zachary
Harris, Anne F
Maitland, Stacy A
Ferreira, Jennifer S
Zhang, Yuanfan
Ma, Shan
Sharma, Rohit B
Gray-Edwards, Heather L
Johnson, Jacob A
Johnson, Aime K
Alonso, Laura C
Punzo, Claudio
Wagner, Kathryn R
Maguire, Casey A
Kotin, Robert M
Martin, Douglas R
Sena-Esteves, Miguel
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5088762
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5088762
Other Identifiers
ISSN
1525-0016
E-ISSN
1525-0024
DOI
10.1038/mt.2016.84
