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Significant glial alterations in response to iron loading in a novel organotypic hippocampal slice c...

Significant glial alterations in response to iron loading in a novel organotypic hippocampal slice c...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5093415

Significant glial alterations in response to iron loading in a novel organotypic hippocampal slice culture model

About this item

Full title

Significant glial alterations in response to iron loading in a novel organotypic hippocampal slice culture model

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2016-11, Vol.6 (1), p.36410, Article 36410

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Aberrant iron deposition in the brain is associated with neurodegenerative disorders including Multiple Sclerosis, Alzheimer’s disease and Parkinson’s disease. To study the collective response to iron loading, we have used hippocampal organotypic slices as a platform to develop a novel
ex vivo
model of iron accumulation. We demonstrated diffe...

Alternative Titles

Full title

Significant glial alterations in response to iron loading in a novel organotypic hippocampal slice culture model

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5093415

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5093415

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/srep36410

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