RNA splicing factors as oncoproteins and tumour suppressors
RNA splicing factors as oncoproteins and tumour suppressors
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Key Points
Genetic and functional data indicate that RNA splicing factors can act as oncoproteins as well as tumour suppressors.
A subset of RNA splicing factors are recurrent targets of specific point mutations in cancer. Many other splicing factors exhibit dysregulated expression in cancer.
In many cases, recurrent spliceosomal mutations...
Alternative Titles
Full title
RNA splicing factors as oncoproteins and tumour suppressors
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5094465
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5094465
Other Identifiers
ISSN
1474-175X
E-ISSN
1474-1768
DOI
10.1038/nrc.2016.51
