Different activation signals induce distinct mast cell degranulation strategies
Different activation signals induce distinct mast cell degranulation strategies
About this item
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Author / Creator
Gaudenzio, Nicolas , Sibilano, Riccardo , Marichal, Thomas , Starkl, Philipp , Reber, Laurent L. , Cenac, Nicolas , McNeil, Benjamin D. , Dong, Xinzhong , Hernandez, Joseph D. , Sagi-Eisenberg, Ronit , Hammel, Ilan , Roers, Axel , Valitutti, Salvatore , Tsai, Mindy , Espinosa, Eric and Galli, Stephen J.
Publisher
United States: American Society for Clinical Investigation
Journal title
Language
English
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Publication information
Publisher
United States: American Society for Clinical Investigation
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Scope and Contents
Contents
Mast cells (MCs) influence intercellular communication during inflammation by secreting cytoplasmic granules that contain diverse mediators. Here, we have demonstrated that MCs decode different activation stimuli into spatially and temporally distinct patterns of granule secretion. Certain signals, including substance P, the complement anaphylatoxi...
Alternative Titles
Full title
Different activation signals induce distinct mast cell degranulation strategies
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5096814
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5096814
Other Identifiers
ISSN
0021-9738,1558-8238
E-ISSN
1558-8238
DOI
10.1172/JCI85538
