The rLrp of Mycobacterium tuberculosis inhibits proinflammatory cytokine production and downregulate...
The rLrp of Mycobacterium tuberculosis inhibits proinflammatory cytokine production and downregulates APC function in mouse macrophages via a TLR2-mediated PI3K/Akt pathway activation-dependent mechanism
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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We demonstrate that Mycobacterium tuberculosis recombinant leucine-responsive regulatory protein （rLrp） inhibits lipopolysaccharide （LPS）-induced tumor necrosis factor alpha （TNF-a）, interleukin-6, and interleukin-12 production and blocks the nuclear translocation of subunits of the nuclear-receptor transcription factor NF-KB （Nuclear factor-kappa...
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Full title
The rLrp of Mycobacterium tuberculosis inhibits proinflammatory cytokine production and downregulates APC function in mouse macrophages via a TLR2-mediated PI3K/Akt pathway activation-dependent mechanism
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5101441
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5101441
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ISSN
1672-7681
E-ISSN
2042-0226
DOI
10.1038/cmi.2015.58
