Tetramethylpyrazine nitrone, a multifunctional neuroprotective agent for ischemic stroke therapy
Tetramethylpyrazine nitrone, a multifunctional neuroprotective agent for ischemic stroke therapy
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
TBN, a novel tetramethylpyrazine derivative armed with a powerful free radical-scavenging nitrone moiety, has been reported to reduce cerebral infarction in rats through multi-functional mechanisms of action. Here we study the therapeutic effects of TBN on non-human primate model of stroke. Thirty male
Cynomolgus
macaques were subjected to st...
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Full title
Tetramethylpyrazine nitrone, a multifunctional neuroprotective agent for ischemic stroke therapy
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5107909
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5107909
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/srep37148
