Glycation potentiates neurodegeneration in models of Huntington’s disease
Glycation potentiates neurodegeneration in models of Huntington’s disease
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Protein glycation is an age-dependent posttranslational modification associated with several neurodegenerative disorders, including Alzheimer’s and Parkinson’s diseases. By modifying amino-groups, glycation interferes with folding of proteins, increasing their aggregation potential. Here, we studied the effect of pharmacological and genetic manipul...
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Full title
Glycation potentiates neurodegeneration in models of Huntington’s disease
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5114697
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5114697
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/srep36798
