Tryptophan hydroxylase 1 and 5-HT7 receptor preferentially expressed in triple-negative breast cance...
Tryptophan hydroxylase 1 and 5-HT7 receptor preferentially expressed in triple-negative breast cancer promote cancer progression through autocrine serotonin signaling
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Publisher
London: BioMed Central Ltd
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Language
English
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London: BioMed Central Ltd
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Background Triple-negative breast cancer (TNBC) has a high risk of relapse and there are few chemotherapy options. Although 5-hydroxytryptamine (5-HT, serotonin) signaling pathways have been suggested as potential targets for anti-cancer drug development, the mechanism responsible for the action of 5-HT in TNBC remains unknown. Methods Quantitative...
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Tryptophan hydroxylase 1 and 5-HT7 receptor preferentially expressed in triple-negative breast cancer promote cancer progression through autocrine serotonin signaling
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5117586
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5117586
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ISSN
1476-4598
E-ISSN
1476-4598
DOI
10.1186/s12943-016-0559-6
