p53 isoform Δ133p53 promotes efficiency of induced pluripotent stem cells and ensures genomic integr...
p53 isoform Δ133p53 promotes efficiency of induced pluripotent stem cells and ensures genomic integrity during reprogramming
About this item
Full title
Author / Creator
Gong, Lu , Pan, Xiao , Chen, Haide , Rao, Lingjun , Zeng, Yelin , Hang, Honghui , Peng, Jinrong , Xiao, Lei and Chen, Jun
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Human induced pluripotent stem (iPS) cells have great potential in regenerative medicine, but this depends on the integrity of their genomes. iPS cells have been found to contain a large number of
de novo
genetic alterations due to DNA damage response during reprogramming. Thus, to maintain the genetic stability of iPS cells is an important g...
Alternative Titles
Full title
p53 isoform Δ133p53 promotes efficiency of induced pluripotent stem cells and ensures genomic integrity during reprogramming
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5118801
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5118801
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/srep37281
