Cancer somatic mutations cluster in a subset of regulatory sites predicted from the ENCODE data
Cancer somatic mutations cluster in a subset of regulatory sites predicted from the ENCODE data
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Publisher
England: BioMed Central Ltd
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Language
English
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England: BioMed Central Ltd
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Scope and Contents
Contents
Transcriptional regulation of gene expression is essential for cellular differentiation and function, and defects in the process are associated with cancer. The ENCODE project has mapped potential regulatory sites across the complete genome in many cell types, and these regions have been shown to harbour many of the somatic mutations that occur in...
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Cancer somatic mutations cluster in a subset of regulatory sites predicted from the ENCODE data
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5123355
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5123355
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ISSN
1476-4598
E-ISSN
1476-4598
DOI
10.1186/s12943-016-0560-0
