Genome-scale high-resolution mapping of activating and repressive nucleotides in regulatory regions
Genome-scale high-resolution mapping of activating and repressive nucleotides in regulatory regions
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Publisher
New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Contents
The activating and repressing nucleotides of regulatory regions are identified at a genome-wide scale using tiling reporter assays.
Massively parallel reporter assays (MPRAs) enable nucleotide-resolution dissection of transcriptional regulatory regions, such as enhancers, but only few regions at a time. Here we present a combined experimental an...
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Full title
Genome-scale high-resolution mapping of activating and repressive nucleotides in regulatory regions
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5125825
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5125825
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ISSN
1087-0156
E-ISSN
1546-1696
DOI
10.1038/nbt.3678
