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Effects of trimethylamine N-oxide and urea on DNA duplex and G-quadruplex

Effects of trimethylamine N-oxide and urea on DNA duplex and G-quadruplex

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5127293

Effects of trimethylamine N-oxide and urea on DNA duplex and G-quadruplex

About this item

Full title

Effects of trimethylamine N-oxide and urea on DNA duplex and G-quadruplex

Publisher

United States: Taylor & Francis

Journal title

Science and technology of advanced materials, 2016-01, Vol.17 (1), p.753-759

Language

English

Formats

Publication information

Publisher

United States: Taylor & Francis

More information

Scope and Contents

Contents

We systematically investigated effects of molecular crowding with trimethylamine N-oxide (TMAO) as a zwitterionic and protective osmolyte and urea as a nonionic denaturing osmolyte on conformation and thermodynamics of the canonical DNA duplex and the non-canonical DNA G-quadruplex. It was found that TMAO and urea stabilized and destabilized, respe...

Alternative Titles

Full title

Effects of trimethylamine N-oxide and urea on DNA duplex and G-quadruplex

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5127293

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5127293

Other Identifiers

ISSN

1468-6996

E-ISSN

1878-5514

DOI

10.1080/14686996.2016.1243000

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