Effects of trimethylamine N-oxide and urea on DNA duplex and G-quadruplex
Effects of trimethylamine N-oxide and urea on DNA duplex and G-quadruplex
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Publisher
United States: Taylor & Francis
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Language
English
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Publisher
United States: Taylor & Francis
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Contents
We systematically investigated effects of molecular crowding with trimethylamine N-oxide (TMAO) as a zwitterionic and protective osmolyte and urea as a nonionic denaturing osmolyte on conformation and thermodynamics of the canonical DNA duplex and the non-canonical DNA G-quadruplex. It was found that TMAO and urea stabilized and destabilized, respe...
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Full title
Effects of trimethylamine N-oxide and urea on DNA duplex and G-quadruplex
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5127293
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5127293
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ISSN
1468-6996
E-ISSN
1878-5514
DOI
10.1080/14686996.2016.1243000