Disentangling the roles of cholesterol and CD59 in intermedilysin pore formation
Disentangling the roles of cholesterol and CD59 in intermedilysin pore formation
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
The plasma membrane provides an essential barrier, shielding a cell from the pressures of its external environment. Pore-forming proteins, deployed by both hosts and pathogens alike, breach this barrier to lyse target cells. Intermedilysin is a cholesterol-dependent cytolysin that requires the human immune receptor CD59, in addition to cholesterol,...
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Full title
Disentangling the roles of cholesterol and CD59 in intermedilysin pore formation
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5133593
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5133593
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/srep38446