Autophagy requires poly(adp-ribosyl)ation-dependent AMPK nuclear export
Autophagy requires poly(adp-ribosyl)ation-dependent AMPK nuclear export
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
AMPK is a central energy sensor linking extracellular milieu fluctuations with the autophagic machinery. In the current study we uncover that Poly(ADP-ribosyl)ation (PARylation), a post-translational modification (PTM) of proteins, accounts for the spatial and temporal regulation of autophagy by modulating AMPK subcellular localisation and activati...
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Full title
Autophagy requires poly(adp-ribosyl)ation-dependent AMPK nuclear export
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5136490
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5136490
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ISSN
1350-9047
E-ISSN
1476-5403
DOI
10.1038/cdd.2016.80
