Sensitisation of an Azole-Resistant Aspergillus fumigatus Strain containing the Cyp51A-Related Mutat...
Sensitisation of an Azole-Resistant Aspergillus fumigatus Strain containing the Cyp51A-Related Mutation by Deleting the SrbA Gene
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Azoles are widely used for controlling fungal growth in both agricultural and medical settings. The target protein of azoles is CYP51, a lanosterol 14-α-demethylase involved in the biosynthesis of ergosterol. Recently, a novel azole resistance mechanism has arisen in pathogenic fungal species
Aspergillus fumigatus
. Resistant strains contain...
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Full title
Sensitisation of an Azole-Resistant Aspergillus fumigatus Strain containing the Cyp51A-Related Mutation by Deleting the SrbA Gene
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5146965
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5146965
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/srep38833
