p53 activates miR-192-5p to mediate vancomycin induced AKI
p53 activates miR-192-5p to mediate vancomycin induced AKI
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Pathogenic role of p53 in AKI remains controversial and the underlying mechanism is unclear. Here, we tested whether the inhibition of p53 may ameliorate vancomycin (VAN) induced acute kidney injury (AKI). Mice with p53 knock out (p53-KO) were resistant to VAN induced AKI, indicated by the analysis of renal function, histology, and apoptosis. Mecha...
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Full title
p53 activates miR-192-5p to mediate vancomycin induced AKI
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5150818
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5150818
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/srep38868
