p120-Catenin Is Critical for the Development of Invasive Lobular Carcinoma in Mice
p120-Catenin Is Critical for the Development of Invasive Lobular Carcinoma in Mice
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Publisher
New York: Springer US
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Language
English
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New York: Springer US
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Contents
Loss of E-cadherin expression is causal to the development of invasive lobular breast carcinoma (ILC). E-cadherin loss leads to dismantling of the adherens junction and subsequent translocation of p120-catenin (p120) to the cytosol and nucleus. Although p120 is critical for the metastatic potential of ILC through the regulation of Rock-dependent an...
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Full title
p120-Catenin Is Critical for the Development of Invasive Lobular Carcinoma in Mice
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5159444
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5159444
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ISSN
1083-3021
E-ISSN
1573-7039
DOI
10.1007/s10911-016-9358-3