Comprehensive phenotypic analysis of knockout mice deficient in cyclin G1 and cyclin G2
Comprehensive phenotypic analysis of knockout mice deficient in cyclin G1 and cyclin G2
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Author / Creator
Ohno, Shouichi , Ikeda, Jun-ichiro , Naito, Yoko , Okuzaki, Daisuke , Sasakura, Towa , Fukushima, Kohshiro , Nishikawa, Yukihiro , Ota, Kaori , Kato, Yorika , Wang, Mian , Torigata, Kosuke , Kasama, Takashi , Uchihashi, Toshihiro , Miura, Daisaku , Yabuta, Norikazu , Morii, Eiichi and Nojima, Hiroshi
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Cyclin G1 (CycG1) and Cyclin G2 (CycG2) play similar roles during the DNA damage response (DDR), but their detailed roles remain elusive. To investigate their distinct roles, we generated knockout mice deficient in CycG1 (G1KO) or CycG2 (G2KO), as well as double knockout mice (DKO) deficient in both proteins. All knockouts developed normally and we...
Alternative Titles
Full title
Comprehensive phenotypic analysis of knockout mice deficient in cyclin G1 and cyclin G2
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5159814
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5159814
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/srep39091
