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Nuclear DNA damage signalling to mitochondria in ageing

Nuclear DNA damage signalling to mitochondria in ageing

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5161407

Nuclear DNA damage signalling to mitochondria in ageing

About this item

Full title

Nuclear DNA damage signalling to mitochondria in ageing

Publisher

London: Nature Publishing Group UK

Journal title

Nature reviews. Molecular cell biology, 2016-05, Vol.17 (5), p.308-321

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Key Points
Mitochondrial dysfunction and genomic instability are two hallmarks of ageing.
Nuclear DNA damage accumulates with ageing and contributes to ageing-associated diseases. Signalling from the nucleus to mitochondria (NM signalling) has a crucial role in regulating mitochondrial function and ageing.
Three major NM signalling pathway...

Alternative Titles

Full title

Nuclear DNA damage signalling to mitochondria in ageing

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5161407

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5161407

Other Identifiers

ISSN

1471-0072

E-ISSN

1471-0080

DOI

10.1038/nrm.2016.14

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