A PGC1α-mediated transcriptional axis suppresses melanoma metastasis
A PGC1α-mediated transcriptional axis suppresses melanoma metastasis
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Full title
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Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
PGC1α suppresses melanoma metastasis and promotes growth and survival in primary tumours, whilst inhibition of PGC1α induces increased invasion and metastasis.
PGC1α suppression of metastasis
Tumour progression is associated with reprogramming of the normal metabolic processes. But do metabolic regulatory circuits affect cancer metastasis? Pe...
Alternative Titles
Full title
A PGC1α-mediated transcriptional axis suppresses melanoma metastasis
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5161587
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5161587
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature19347
