Germinal centre hypoxia and regulation of antibody qualities by a hypoxia response system
Germinal centre hypoxia and regulation of antibody qualities by a hypoxia response system
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Hypoxia in germinal centres regulates B cell class switching via its effects on mTOR complex 1 and activation-induced cytosine deaminase activity.
Oxygen restriction in germinal centres
Oxygen delivery and local hypoxia have been extensively studied in solid tumours in relation to immunobiology of cancer, but little is known about the microan...
Alternative Titles
Full title
Germinal centre hypoxia and regulation of antibody qualities by a hypoxia response system
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5161594
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5161594
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature19334
