Development of an in-vivo active reversible butyrylcholinesterase inhibitor
Development of an in-vivo active reversible butyrylcholinesterase inhibitor
About this item
Full title
Author / Creator
Košak, Urban , Brus, Boris , Knez, Damijan , Šink, Roman , Žakelj, Simon , Trontelj, Jurij , Pišlar, Anja , Šlenc, Jasna , Gobec, Martina , Živin, Marko , Tratnjek, Larisa , Perše, Martina , Sałat, Kinga , Podkowa, Adrian , Filipek, Barbara , Nachon, Florian , Brazzolotto, Xavier , Więckowska, Anna , Malawska, Barbara , Stojan, Jure , Raščan, Irena Mlinarič , Kos, Janko , Coquelle, Nicolas , Colletier, Jacques-Philippe and Gobec, Stanislav
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Alzheimer’s disease (AD) is characterized by severe basal forebrain cholinergic deficit, which results in progressive and chronic deterioration of memory and cognitive functions. Similar to acetylcholinesterase, butyrylcholinesterase (BChE) contributes to the termination of cholinergic neurotransmission. Its enzymatic activity increases with the di...
Alternative Titles
Full title
Development of an in-vivo active reversible butyrylcholinesterase inhibitor
Authors, Artists and Contributors
Author / Creator
Brus, Boris
Knez, Damijan
Šink, Roman
Žakelj, Simon
Trontelj, Jurij
Pišlar, Anja
Šlenc, Jasna
Gobec, Martina
Živin, Marko
Tratnjek, Larisa
Perše, Martina
Sałat, Kinga
Podkowa, Adrian
Filipek, Barbara
Nachon, Florian
Brazzolotto, Xavier
Więckowska, Anna
Malawska, Barbara
Stojan, Jure
Raščan, Irena Mlinarič
Kos, Janko
Coquelle, Nicolas
Colletier, Jacques-Philippe
Gobec, Stanislav
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5175178
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5175178
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/srep39495
